Silicycle Functionalised Silicas
Silicycle Product Brochures
SiliaMetS Metal Scavengers
SiliaMetS - silica gels functionalised with chemical handles for reacting with and trapping metals present in your reactions.
Which SiliaMetS agent do I need?
Decide which metal you wish to scavenge.
Use this chart to determine which SiliaMetS agents are compatible with your metal.
Watch this video to see how easy it is to use the SiliaMetS agents.
Why SiliaMetS?
Compatible with any organic/aqueous solvent (pH 2-12)
Mechanically stable under vigorous stirring
Remove using simple filtration
Microwave compatible
No loss of API
Fast kinetics/low-cost
Literature example:
SiliaMetS Cysteine
5 g / £39
(incl. VAT)
R80530B
SiliaMetS TAAcOH
5 g / £39
(incl. VAT)
R69030B
SiliaMetS DMT
5 g / £39
(incl. VAT)
R79030B
SiliaMetS TAAcONa
5 g / £39
(incl. VAT)
R69230B
SiliaMetS Imidazole
5 g / £39
(incl. VAT)
R79230B
SiliaMetS Thiol
5 g / £39
(incl. VAT)
R51030B
SiliaMetS Triamine
5 g / £39
(incl. VAT)
R48030B
SiliaMetS Thiourea
5 g / £39
(incl. VAT)
R69530B
Universal Scavenger Kit (K30730B): 5g of all eight scavengers shown above for £285 (incl. VAT and shipping)
Larger pack sizes available. Please enquire for 10 g, 25 g, 50 g, 100 g, 250 g, 500 g and 1 kg.
SiliaBond Peptide Synthesis Reagents and Organic Scavengers
SiliaBond - silica gels functionalised for use as synthetic reagents or as organic scavengers.
Which SiliaBond agent do I need?
Use this chart to determine which SiliaMetS agents are compatible with your metal.
Why SiliaBond?
Easy isolation of product through filtration / no API loss
Can eliminate the need for column chromatographic purification
Mechanically stable under vigorous stirring - no leaching
Remove using simple filtration
Thermally stable
Fast kinetics/low-cost
Literature example:
Rapid analogue generation through parallel synthesis enabled by the use of SiliaBond-carbodiimide and Siliabond-carbonate for amide couplings: https://www.pnas.org/doi/full/10.1073/pnas.1015255108
SiliaBond Carbodiimide
10 g / £90 (incl. VAT)
R70530B
SiliaBond DMAP
10 g / £130 (incl. VAT)
R75630B
SiliaBond Carbonate
10 g / £80 (incl. VAT)
R66030B
SiliaBond Amine (WAX)
10 g / £55 (incl. VAT)
R52130B
SiliaBond Piperazine
10 g / £81 (incl. VAT)
R60530B
SiliaBond Carboxylic Acid (WCX)
R70030B
10 g / £55 (incl. VAT)
SiliaBond Tosic
Acid (SCX)
R60530B
10 g / £55 (incl. VAT)
SiliaBond Propylsulfonic Acid (SCX-2)
R51230B
5 g / £55 (incl. VAT)
SiliaBond carbodiimide - synthesis of amides, esters, and activated esters.
SiliaBond DMAP - use analogously to 4-dimethylaminopyridine as a nucleophilic catalyst for acylation, amidation or acetylation.
SiliaBond carbonate - silica bound analogue of tetramethyl ammonium carbonate. Use as a general base to quench a reaction, scavenge acids and excess HOBt in amide coupling reactions.
SiliaBond amine - use as a weak anion exchanger or to scavenge acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles.
SiliaBond Piperazine - deprotecting Fmoc and Bsmoc amino protecting groups and as a solid-phase Knoevenagel catalyst. May also be used to scavenge electrophiles.
SiliaBond carboxylic acid - use as a weak cation exchanger or to scavenge amines or carbonates, and quench alkoxides and organometallic reagents.
SiliaBond tosic acid - use as a strong cation exchanger or as a solid-supported strong acid with a pka <1. Can scavenge amines and other basic functionalities, including weakly basic anilines, borohydrides, and metals such as Ni and Ag. It can also be used as an acid catalyst for organic reactions. Serves as an alternative for quenching reactions instead of aqueous/organic soluble acids.
SiliaBond propylsulfonic acid - use as a strong cation exchanger or to scavenge amines and other basic functionalities.
Larger pack sizes available. Please enquire for 10 g, 25 g, 50 g, 100 g, 250 g, 500 g and 1 kg.
VERITAS SCIENTIFIC is an authorised UK dealer for the ECOM range of chromatography equipment and Silicycle range of functionalised silica gels. Leveraging connections with European manufactures we can also facilitate the custom design and manufacture of pumps, valves, large scale columns, flow cells and UV-VIS flow detectors to your specifications. We also market a range of chromatographic separation units suitable for analytical, preparative and pilot plant scale.
Dr Aditya Raymond Thawani
Email: raymond@veritasscientific.net
Telephone: +44 20 8133 5293
Address: Hammersmith and Fulham, London, United Kingdom